Potentiated sulfonamide injectable preparation

Details Potentiated sulfonamide injectable preparation Potentiated sulfonamide injectable preparation

1980-06-11

1982-06-01

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

424 36, 424 38, 424251, A61K 942, A61K 31505, A61K 31625

Patent

active

043327966

ABSTRACT:
Potentiated sulfonamide compositions useful for intramuscular injection are disclosed which comprise mixtures of alkali metal sulfonamides with microcrystalline potentiators wherein the microcrystals have been coated with mixtures of phospholipids and non-ionic surfactants. The compositions are advantageous in that they can be used extemporaneously by addition of sterile water for injection, the resulting aqueous preparation is stable for long periods of time and upon use the compositions are characterized by syringeability and lack of irritation at the injection site.

REFERENCES:
patent: 2867565 (1959-01-01), Feinstone
patent: 3551564 (1970-12-01), Klaui et al.
patent: 3574833 (1971-04-01), Arnold et al.
patent: 4031214 (1977-06-01), Easterbrook

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