Potent synthetic atrial peptide analogs

Details Potent synthetic atrial peptide analogs Potent synthetic atrial peptide analogs

1986-05-09

1988-01-26

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 13, 530326, A61K 3724, C07K 710

Patent

active

047217049

ABSTRACT:
Biologically active atrial peptide analogs having 21 or 22 amino acid residues are provided with potent diuretic and natriuretic activities, and which lower blood pressure. These analogs have a .beta.-mercaptopropanoic acid derivative moiety at the N-terminus and have D-Alanine at the 3 position of the amino acid sequence.

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