Potent, simplified derivatives of pateamine A

Details Potent, simplified derivatives of pateamine A Potent, simplified derivatives of pateamine A

2007-06-12

2007-06-12

Coleman, Brenda (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S375000, C514S393000, C540S456000, C540S460000, C540S468000, C548S201000

Reexamination Certificate

active

10388257

ABSTRACT:
The present invention provides a compound of Formula I, all of its related stereoisomers, and their pharmaceutically acceptable salts, wherein A—B, K, Q, X, Y, Z, R and R1 are as defined in Claim1. The present invention also provides processes for the preparation thereof, the use thereof in treating immune mediated disease and conditions, and pharmaceutical compositions for use in such therapy

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