Potent indole-3-carbinol-derived antitumor agents

Details Potent indole-3-carbinol-derived antitumor agents Potent indole-3-carbinol-derived antitumor agents

2008-05-09

2010-10-05

Saeed, Kamal A (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S491000

Reexamination Certificate

active

07807705

ABSTRACT:
Compounds and methods for treating cancer and inducing apoptosis in unwanted rapidly proliferating cells. The compounds are shown in formula I:wherein X is hydroxyl or amino; Y is carboxyl or sulfonyl; R1, R2, R3, and R4can be the same or different and are selected from hydrogen, halogen, methoxy, trifluoromethyl, hydroxyl and combinations thereof, R5, R6, and R7may be the same or different and are selected from hydrogen, chloro, bromo, nitro, phenyl, amino, methoxy, and combinations thereof, and derivatives or metabolites thereof.

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