Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2001-01-11
2008-09-30
Guzo, David (Department: 1636)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007200, C435S007310
Reexamination Certificate
active
07429449
ABSTRACT:
The invention relates to processes for identifying inhibitors and activators of eukaryotic potassium channels, in which a mutatedS. cerevisiaecell is used whose endogenous potassium channels TRK1, TRK2 and TOK1 are not expressed functionally, but which expresses heterologously a eukaryotic potassium channel to be studied. Other subject matters of the invention are mutatedS. cerevisiaecells which do not express TRK1, TRK2 and TOK1, and the preparation and use of these mutatedS. cerevisiaecells.
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Leberer Ekkehard
Leeuw Thomas
Ritscher Allegra
Guzo David
Joike Michele K.
MDIP LLC
SANOFI-AVENTIS Deutschland GmbH
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