Potassium channel blocking agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S257000, C540S472000

Reexamination Certificate

active

06878701

ABSTRACT:
Compounds of Formula I:wherein A and B are linking groups; R1, R2, R3and R4are defined moieties. An exemplary compound is:These compounds function as potassium channel blocking agents, and can be used in a wide variety of pharmaceutical compositions for the treatment of a wide variety of diseases.

REFERENCES:
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patent: 5760230 (1998-06-01), Schohe-Loop et al.
patent: 5874438 (1999-02-01), Schohe-Loop et al.
patent: 9748705 (1997-12-01), None
patent: 0001676 (2000-01-01), None
STN International, Soichi et al., Mem. Inst. Sci. Ind. Res., Osaka Univ. No. 1986:109563, Document No. 104:104653, (1985), pp. 53-67.
STN International, Mikhailov, A. S. et al., Zh. Obshch. Khim., No. 1996:605017, Document No. 126:31340, (1996), two pages (1 & 2).
STN International, Mikhailov, A. S. et al., Dokl. Akad. Nauk, No. 1999:630451, Document No. 131:351293, (1998), p. 1-A & p. 2-A.
Dimitrios Galanakis et al., J. Med. Chem., vol. 38, 1995 pp. 595-606.

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