Potassium channel blockers and uses thereof

Details Potassium channel blockers and uses thereof Potassium channel blockers and uses thereof

2006-03-15

2011-11-22

Solola, Taofiq A (Department: 1622)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S432000

Reexamination Certificate

active

08063093

ABSTRACT:
The invention relates to compounds of Formula (1) for use in modulating potassium channel activity in cells.

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Levashova I. G., et al., “Reactivity of carbonyl derivatives of phenyl- and diphenylpropane. I. Kinetics of oxime formation from derivatives of furanochromone, dihydroflavanone, and chalcone”,Khimiya Priorodnykh Soedinenii 1: 70-76 (1987), Abstract, Document No. 109:37644.
Martin M., et al., “Synthesis and β-adrenolytic properties of some amino alcohol derivatives of furo [3, 2-g] chrome”,European Journal of Medicinal Chemistry 9(5): 563-570 (1974), Abstract, Document No. 83:9852.
Hamed Abu-Shady & Taito O. Soine, “Experiments with Khellin. II. The Synthesis of 5,6-Dimethoxy-2-methylfuro(2′,3′,7,8)chromone and Its Identity with Isokhellin”,J. Am. Pharm. Assoc. Am. Pharm. Assoc. (Baltimore) 41(8):403-7 (1952).

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