Poststatin and related compounds or salts thereof

Details Poststatin and related compounds or salts thereof Poststatin and related compounds or salts thereof

1992-06-29

1994-10-25

Cashion, Jr., Merrell C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

530330, C07C22900, A61K 3700, A61K 3702, C07K 500

Patent

active

053591380

ABSTRACT:
A novel, biologically active substance, poststatin, has been isolated from a culture medium of microorganism belonging to Streptomyces. The novel substance is a peptide compound having a novel structure, wherein the peptide chains have ketone radicals. Thus substance has a high endopeptidase inhibition activity. It is possible to chemically synthesize poststatin related compound having ketone radicals in the peptide chains. These compounds also have an endopeptidase inhibition activity.

REFERENCES:
patent: 4242256 (1980-12-01), Sharpe et al.
patent: 4613676 (1986-09-01), Fuhrer et al.
patent: 4978759 (1990-12-01), Jouin et al.
Hori et al., Peptides Structure Function, Proceeding of the 9th American Peptide Symposium, pp. 819-822, 1985.
Bender et al., Chem Abst., vol. 108, p. 719, 1988, ab No. 205099.

Affiliated with

Also associated with

Rating

Poststatin and related compounds or salts thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Poststatin and related compounds or salts thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Poststatin and related compounds or salts thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-137052