Postoperative treatment of carcinoma patients

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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424251, 424270, A61K 31455, A61K 31505, A61K 31425

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active

043783643

ABSTRACT:
Cancer patients following surgery are treated to lessen pain, induce a feeling of well-being and increase appetite by administering to the mammal an effective dosage of a non-toxic dithiobis-heterocyclic compound, belonging to the class of thione-forming disulfides, such as 6,6'-dithiodinicotinic acid (CPDS) which is capable of preferentially reacting with peripheral rather than intracellular sulfhydryl groups. In addition to this blocking effect, treatment with compounds of this type also has the effect of modifying the electric charge of cell surfaces. This blocking of peripheral sulfhydryl groups is not accompanied by toxic effects in laboratory mammals or in man.

REFERENCES:
patent: 3698866 (1972-10-01), Grassetti
Chemical Abstracts 70: 95124a, (1969).

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