Post protein hydrolysis removal of a potent ribonuclease...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S014000

Reexamination Certificate

active

07416843

ABSTRACT:
The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.

REFERENCES:
patent: 4693972 (1987-09-01), Mansour et al.
patent: 7303876 (2007-12-01), Greenfield et al.
patent: 2005/0014128 (2005-01-01), Ewert et al.
patent: WO 2005/021799 (2005-03-01), None
Hallick, R.B. et al. “Use of Aurintricarboxylic Acid as an Inhibitor of Nucleases During Nucleic Acid Isolation”Nucleic Acids Research, Sep. 1977, pp. 3055-3064, vol. 4, No. 9.
Kiss, C. et al. “Improved Subtractive Suppression Hybridization Combined with High Density cDNA Array Screening Identifies Differentially Expressed Viral And Cellular Genes”Journal of Virological Methods, 2003, pp. 195-203, vol. 107.
Leal-Klevezas, D.S. et al. “Single-Step PCR for Detection ofBrucellaspp. from Blood and Milk of Infected Animals”Journal of Clinical Microbiology, Dec. 1995, pp. 3087-3090, vol. 33, No. 12.
Lonneborg, A. et al. “Reliable and Reproductive Method to Extract High-Quality RNA from Plant Tissues Rich in Secondary Metabolites”Biotechniques, Oct. 2000, pp. 714-718, vol. 29, No. 4.
Park, Y.D. et al. “Photopolymerized Hyaluronic Acid-Based Hydrogels and Interpenetrating Networks”Biomaterials, 2003, pp. 893-900, vol. 24, No. 6.
“Polymerase Chain Reaction for Rapid Diagnosis of Candidemia”Bull Acad Mil Med Science, Sep. 1998, vol. 22, No. 3.
Archibald, L.K. et al. “Comparison of Bactec MYCO/F Lytic and Wampole Isolator 10 (Lysis-Centrifugation) Systems for Detection of Bacteremia, Mycobacteremia, and Fungermia in a Developing Country”Journal of Clinical Micro., Aug. 2000, pp. 2994-2997, vol. 38, No. 8.
Brannon, P. et al. “Clinical Comparison of Lysis-Centrifugation and Radiometric Resin Systems for Blood Culture”Journal of Clinical Microbiology, Nov. 1986, pp. 886-887, vol. 24, No. 5.
Siersema, P.D. et al. “Blood Culture Bottles are Superior to Lysis-Centrifugation Tubes for Bacteriological Diagnosis of Spontaneous Bacterial Peritonitis”Journal of Clinical Microbiology, Mar. 1992, pp. 667-669, vol. 30, No. 3.
Hamilton, D.J. et al. “Effect of Delay in Processing on Lysis-Centriguation Blood Culture Results from Marrow Transplant Patients”Journal of Clinical Microbiology, Jul. 1989, pp. 1588-1593, vol. 27, No. 7.
Bernhardt, M. et al. “Detection of Bacteria in Blood by Centrifugation and Filtration”Journal of Clinical Microbiology, Mar. 1991, pp. 422-425, vol. 29, No. 3.
Hoffman, S.L. et al. “Bone Marrow Aspirate Culture Superior to Streptokinase Clot Culture and 8 ML 1:10 Blood-to-Broth Ration Blood Culture for Diagnosis of Typhoid Fever”American Society of Tropical Medicine&Hygiene, 1986, pp. 836-839, vol. 35, No. 4.
Al-Soud, W.A. et al. “Purfication and Characterization of PCR-Inhibitory Components in Blood Cells”Journal of Clinical Microbiology, Feb. 2000, pp. 485-493, vol. 39, No. 2.
Morata, P. et al. “Diagnostic Yield of a PCR Assay in Focal Complications of Brucellosis”Journal of Clinical Microbiology, Oct. 2001, pp. 3743-3746, vol. 39, No. 10.
Li, J. et al. “Effects of Volume and Periodicity on Blood Cultures”Journal of Clinical Microbiology. Nov. 1994, pp. 2829-2831, vol. 32, No. 11.
Queipo-Ortuno, M.I. et al. “Rapid Diagnosis of Human Brucellosis by Peripheral-Blood PCT Assay”Journal of Clinical Microbiology, Nov. 1997, pp. 2927-2930, vol. 35, No. 11.
Gamboa, F. et al. “Detection and Identification of Mycobacteria by Amplification of RNA and DNA in Pretreated Blood and Bone Marrow Aspirates by a Simple Lysis Method”Journal of Clinical Microbiology, Aug. 1997, pp. 2124-2128, vol. 35, No. 8.
Morata, P et al. “Posttreatment Follow-Up of Brucellosis by PCR Assay”Journal of Clinical Microbiology, Dec. 1999, pp. 4163-4166, vol. 37, No. 12.
Cassels, R. et al. “The Interaction of Streptokinase-Plasminogen Activator Complex, Tissue-Type Plasminogen Activator, Urokinase and their Acylated Derivatives with Fibrin and Cyanogen Bromide Digest of Fibrinogen: Relationship to Fibrinolytic Potency In Vitro”Journal of Biochemistry, 1987, pp. 395-400, vol. 247, No. 2.
Castellino, F.J. et al. “Biochemistry of Human Plasminogen”Seminars in Thrombosis&Hemostasis, 1984, pp. 18-23, vol. 10, No. 1.
Miles, L.A. et al. “Binding and Activatio of Plasminogen on the Platelet Surface”Journal of Biological Chemistry, Apr. 1985, pp. 4303-4311, vol. 260, No. 7.
Gaffney, P.J. et al. “Plasma Fibrinogen and its Fragments during Streptokinase Treatment”British Journal of Haematology, 1974, pp. 285-293, vol. 26, No. 2.
Malin, G. et al. “Effect of Tetrahydropyrimidine Derivatives on Protein-Nucleic Acids Interaction: Type II Restriction Endonucleases as a Model System”Journal of Biological Chemistry, Mar. 12, 1999, pp. 6920-6929, vol. 274, No. 11.
Malin, G. et al. “Induction of Synthesis of Tetrahydropyrimidine Derivatives in Steptomyces Strains and their Effect ofEscherichia Coliin Response to Osmotic and Heat Stress”Journal of Bacteriology, Jan. 1996, pp. 385-395, vol. 178, No. 2.
Cottrell, R.C. “Phospholipase A2 from Bee Venom”Methods in Enzymology, 1981, pp. 698-702, vol. 71.
Nguyen, P.D. et al. “Thrombolysis using Liposomal-Encapsulated Streptokinase: An In Vitro Study”Proc Soc Exp Biol Med, 1989, pp. 261-269, vol. 192, No. 3.
Cao, Y.Z. et al. “The Purification and Characterization of a Phospholipase A in Hampster Heart Cystol for the Hydrolysis of Phosphatidylcholine”Journal of Biological Chemistry, Dec. 15, 1987, pp. 16927-16935, vol. 262, No. 35.
Fisher, A.B. et al. “Lysosomal-Type PLA2 & Turnover of Alveolar DPPC”Am J Physiol Lung Cell Mol Physiol, Apr. 2001, pp. 748-754, vol. 280, No. 4.
Chen, J.W. et al. “1-Cys Peroxiredoxin, a Bifunctional Enzyme with Glutathione Peroxidase and Phospholipase A2 Activities”Journal of Biological Chemistry, Sep. 2000, pp. 28421-28427, vol. 275, No. 37.
Shipolini, R.A. et al. “Phospholipase A from Bee Venom”Journal of Biological Chemistry, 1971, pp. 459-468, vol. 20, No. 4.
Menashe, M. et al. “Hydrolysis of Dipalmitoylphosphatidylcholine Small Unilamellar Vesicles by Porcine Pancreatic Phospholipase A2”Journal of Biological Chemistry, 1986, pp. 5328-5333, vol. 261, No. 12.
Molloy, M.P. et al. “Proteomic Analysis of theEscherichia coliOuter Membrane”Eur J Biochem, 2000, pp. 2871-2881, vol. 267, No. 10.
Sponer, J. et al. “Electronic Properties, Hydrogen Bonding, Stacking, and Cation Binding of DNA and RNA Bases”Biopolymers, 2001-2002, pp. 3-31, vol. 61, No. 1.
Gonzalez, R.G. et al. “Mechanism of Action of Polymeric Aurintricarboxylic Acid, A Potent Inhibitor of Protein-Nucleic Acid Interactions”Biochemistry, 1980, pp. 4299-4303, vol. 19, No. 18.
Oberbaumer, I. et al. “Detection of RNA on Nothern Blots by Negative Staining with Aurintricarboxylic Acid”Anal Biochem, 1990, pp. 77-79, vol. 185, No. 1.
Givens, J.F. et al. “Inhibition of RNA-Directed DNA Polymerase by Aurintricarboxylic Acid”Nucleic Acids Research, Feb. 1976, pp. 405-418, vol. 3, No. 2.
Guo, Z. et al. “M(r) 6,400 Aurin Tricarboxylic Acid Directly Activates Platelets”Thrombosis Research, 1993, pp. 77-88, vol. 71, No. 1.
Gonzalez, R.G. et al. “Fractionation and Structural Elucidation of the Active Components of Aurintricarboylic Acid, A Potent Inhibitor of Protein Nucleic Acid Interactions”Biochim Biophys Acta., pp. 534-545, vol. 562, No. 3.
Birnboim, H. C. “Rapid Extraction of H

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