Post-labeling stabilization of radiolabeled proteins and peptide

Details Post-labeling stabilization of radiolabeled proteins and peptide Post-labeling stabilization of radiolabeled proteins and peptide

1997-02-03

2000-05-23

Dees, Jose' G.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Attached to antibody or antibody fragment or immunoglobulin;...

4241301, 4241411, 424 111, 424 165, 424 169, A61K 5100, A61M 3614

Patent

active

06066309&

ABSTRACT:
The subject invention relates to the use of ascorbic acid and derivatives thereof in stabilizing radiolabeled proteins and peptides against oxidation loss of radiolabel and autoradiolysis. Ascorbic acid is added after radiolabeling, including any required incubation period, but prior to patient administration.

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