Positively charged membrane

Details Positively charged membrane Positively charged membrane

2005-02-08

2005-02-08

Kim, John (Department: 1723)

Liquid purification or separation

Filter

Supported, shaped or superimposed formed mediums

C210S435000, C210S488000, C210S493100, C210S497010, C210S500210, C210S500370, C210S500380

Reexamination Certificate

active

06851561

ABSTRACT:
The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.

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