Positive selection sorting of cells

Details Positive selection sorting of cells Positive selection sorting of cells

1983-07-14

1986-11-25

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435240, 435291, C12N 500, C12M 134, C12Q 100

Patent

active

046249150

ABSTRACT:
A method and apparatus for position selection of viable cells based upon differing chemical or physical properties or dynamic processes using a focussed radiant energy beam, such as a laser beam (11) to kill unwanted cells or to isolate wanted cells is described. The apparatus includes microscope means (14) and cell detection means (27) for identifying the cells to be killed or saved and attenuator means (12) for modifying the beam to prevent destruction of cells to be saved.

REFERENCES:
patent: 3712746 (1973-01-01), Bergeron
patent: 3941670 (1976-03-01), Pratt, Jr.
patent: 3984307 (1976-10-01), Kamentsky et al.
patent: 4045772 (1977-08-01), Bouton et al.
patent: 4090128 (1978-05-01), Simpson et al.
patent: 4090921 (1978-05-01), Sawamura et al.
patent: 4172227 (1979-10-01), Tyrer et al.
patent: 4175662 (1979-11-01), Zold
patent: 4204117 (1980-05-01), Aberle et al.
patent: 4209256 (1980-06-01), Faulkner
patent: 4284897 (1981-08-01), Sawamura et al.
patent: 4354114 (1982-10-01), Karnaukhov et al.
patent: 4395397 (1983-07-01), Shapiro
patent: 4513438 (1985-04-01), Graham et al.
Cell Separation: Methods and Selected Applications, Pretlon, II, T. G. et al, ed., Academic Press, New York, pp. 193-198 (1982).
The Coulter.RTM. EPICS.RTM. V System, brochure, Coulter Electronics, Inc., Rev. Apr. 1982.
Higgins et al, 1980, "Selective Cell Destruction and Precise Neurite Transection . . . " J. Neuroscience Methods, v3, pp. 83-99.
Bessis, 1970, "Selective Destruction of Cell Organelles by Laser Beam" Adv. in Biol. and Medical Physics, v13, pp. 209-218.
Koppel, 1979, "Fluorescence Redistribution after Photobleaching" Biophys. J. v28, pp. 281-292.
Koppel, D. E. et al, Biophysics Journal 28:281-291 (1979).
Higgins, et al., J. Neurosc. Meth., 3, 1, 1980.
Lepock, et al., Biochem. Biophys. Res. Comm. 91, 3, 1979.
Berns, in Jour. Cell Biol. 75, 3, 1975.

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