Positive modulators of nicotinic receptors

Details Positive modulators of nicotinic receptors Positive modulators of nicotinic receptors

2005-03-01

2005-03-01

Wilson, James O. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S343000, C548S469000

Reexamination Certificate

active

06861443

ABSTRACT:
The present invention relates to pharmaceutical compositions comprising a positive modulator of a nicotinic receptor agonist, said positive modulator having the capability to increase the efficacy of the said nicotinic receptor agonist.

REFERENCES:
patent: 5135544 (1992-08-01), Grollier et al.
patent: 6077846 (2000-06-01), Qian et al.
patent: 9606098 (1996-02-01), None
patent: 9730998 (1997-08-01), None
patent: 9903859 (1999-01-01), None
patent: PCTSE99/00700 (1999-04-01), None
Kooyman et al., “5-Hydroxyindole slows desensitization of the 5-HT3receptor . . . ” Br. J. Pharmcol, vol. 108, pp. 287-289 (1993).
Schrattenholz et al., “Agonist Responses of Neuronal Nicotinic Acetylcholine . . . ” Molecular Pharmacology, vol. 49, pp. 1-6 (1996).
Krause et al, “Ivermectin: A Positive Allosteric Effector . . . ” Molecular Pharmacology, vol. 53, pp. 283-294, 1998.
Kuntzweiler et al.,Rapid Assessment of Ligand Actions with Nicotinic Acetylcholine Receptors Using Calcium Dynamics and FLIPR, Drug Development Research, Issued May 1, 1998, vol. 44, pp. 14-20, May 1998.
Ospina et al., Calcium Regulation of Agonist Binding to alpha 7-Type Nicotinic Acetylcholine Receptors in Adult and Fetal Rat Hippocampus, Journal of Neurochemistry, vol. 70, No. 3, Issued Mar. 1998.

Affiliated with

Also associated with

Rating

Positive modulators of nicotinic receptors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Positive modulators of nicotinic receptors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Positive modulators of nicotinic receptors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3454257