Positive modulators of nicotinic receptor agonists

Details Positive modulators of nicotinic receptor agonists Positive modulators of nicotinic receptor agonists

2006-06-20

2006-06-20

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S469000

Reexamination Certificate

active

07064143

ABSTRACT:
Compounds of Formula Iwherein R1, R2, R3, R4, R5, W and X as defined in the specification, enantiomers thereof, pharmaceutically-acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially for treatment of conditions associated with reductions in nicotinic transmission. Compounds of the invention enhance the efficacy of agonists at nicotinic receptors.

REFERENCES:
patent: 5690697 (1997-11-01), Samain
patent: 0237781 (1987-09-01), None
patent: 0722941 (1996-07-01), None
patent: 1310235 (1973-03-01), None
patent: WO 9205170 (1992-04-01), None
patent: WO 9311106 (1993-06-01), None
patent: WO 9318026 (1993-09-01), None
patent: WO 9530655 (1995-11-01), None
Goodman & Gilman's, The Pharmaceutical Basis of Therapeutics, 10thEdition, 2001, p. 549.
Phytochemistry, vol. 11, 1972, Yasuyoshi Torigoe et al, “Cytokinin Activity of Azaindene, Azanaphthalene, Naphthalene, and Indole Derivatives”, p. 1623-p. 1630, see compounds (XIII) and (XIV), p. 1625.
Chemical Abstracts, vol. 57 (), (Columbus, Ohio, USA), E. Piers et al, The synthesis of mercaptoindoles, The Abstract No. 15053h, Can. J. Chem. 1962, 40, 511-517.

Affiliated with

Also associated with

Rating

Positive modulators of nicotinic receptor agonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Positive modulators of nicotinic receptor agonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Positive modulators of nicotinic receptor agonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3703446