Positive inotrophic benzothiazole and benzothiophene composition

Details Positive inotrophic benzothiazole and benzothiophene composition Positive inotrophic benzothiazole and benzothiophene composition

1989-04-06

1990-05-29

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514366, 514367, A61K 31425, A61K 3138, A61K 3136

Patent

active

049296361

ABSTRACT:
The invention relates to compounds of the general formula I ##STR1## wherein R.sub.1 represents one up to and including four, the same or different substituents selected from alkyl(1-6 C), alkoxy(1-6 C), hydroxy, halogen, NO.sub.2, CF.sub.3 or the group --NR.sub.5 R.sub.6, whereby two substituents taken together may also represent a methylene-dioxy group,

REFERENCES:
patent: 2775593 (1956-12-01), Behnisch et al.
patent: 4249014 (1981-02-01), Robba et al.
Goodman and Gilman, "The Pharmacological Basin of Therapeutics", 7th Ed., p. 7/6 (1985).
Cheng, "The International Textbook of Cardiology", Pergamon Press, p. 1047 (1986).
Breckenridge, "Drugs in the Management of Heart Disease", MTP Press, p. 159 (1985).
Chemische Berichte, K. Wagner et al., "Synthesis and Reactivity of 2-Alkoxycarbonylbenzothiazole N-Oxides," vol. 106, No. 2 (1973), pp. 639-654.

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