Positive AMPA receptor modulation to enhance brain neurotrophic

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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5142302, A61K 3154, A61K 31535

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active

060309687

ABSTRACT:
Methods for increasing the level of neurotrophic factors and neurotrophic factor receptors in the brain of a mammal afflicted with a pathology which produces neurodegeneration without significant loss of memory or learning comprising administering to a mammal an effective amount of an allosteric upmodulator of .alpha.-amino-3-hydroxy-5-methyl-isoxazole-4-proprionic acid (AMPA) receptors.

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