Surgery – Respiratory method or device
Patent
1979-01-10
1980-11-11
Recla, Henry J.
Surgery
Respiratory method or device
128913, A61M 1600
Patent
active
042326656
ABSTRACT:
This invention relates to the combination of a number of pieces of separate functioning apparatus in order to accomplish the combined purposes of producing medical grade oxygen from air, saturating an inert isotonic liquid with the oxygen, adjusting the temperature of the oxygen saturated liquid to a predetermined temperature, injecting the oxygen saturated liquid into the bottom of the animal lung(s) cavity, circulating the liquid up through the lung(s) cavity by removal of the carbon dioxide saturated liquid at the top of the lung(s) cavity along with displaced from the lung(s) cavity non-miscible, aqueous liquid; separation of nonmiscible liquid, filtering of isotonic liquid for particulate removal, heat sterilization of isotonic liquid as well as stripping of remaining absorbed gases, particularly carbon dioxide (CO.sub.2), cooling and temperature adjusting of isotonic liquid to predetermined desired temperature, and return of isotonic liquid to saturator for resaturation with oxygen and repeat cycle use. Remaining isotonic liquid in the lung(s) cavity, at end of treatment is removed by inverting animal sufficiently to raise the influent tube at bottom of lung(s) cavity above effluent tube and inflating lung(s) cavity with medical grade oxygen gas.
REFERENCES:
Patel et al., Survival and Histopathologic Changes in Lungs of Hamsters Following Synthetic Liquid Breathing, Fed. Proc. vol. 29, No. 5, Oct. 1970, pp. 1740-1745.
Moskowitz, A Mechanical Respirator for Control of Liquid Breathing, Fed. Proc. vol. 29, No. 5, Oct. 1970, pp. 1751-1752.
Rahn, Discussion on Liquid Breathing, Fed. Proc. vol. 29, No. 5, pp. 1753-1754, Oct. 1970.
Clark, Jr. et al., Perfusion of Whole Animals with Perfluorinated Liquid Emulsions Using the Clark Bubble-Defoam Heart Lung Machine, Fed. Proc. vol. 29, No. 5, pp. 1764-1770, Oct. 1970.
Clark, Jr. Epilogue, Fed. Proc., vol. 29, No. 5, p. 1820, Oct. 1970.
Gollan et al., Experimental Pathology After Respiration and Injection of Various Fluorocarbon Liquids, Exp. Med and Surg. vol. 26, No. 4, Dec. 1968, pp. 249-262.
Clark Jr., et al., Survival of Mammals Breathing Organic Liquids Equilibrated with Oxygen at Atmospheric Pressure, Science vol. 152, pp. 1755-1756, Jun. 1966.
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