Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1987-06-08
1990-03-27
Huleatt, Jayme A.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
43525231, 435320, 935 29, 935 31, 935 40, 935 41, 935 72, 935 74, C12N 120, C12N 1500
Patent
active
049120468
ABSTRACT:
Shuttle vector systems are provided for the regulated expression of subject genes in transformed hosts. A promoter/operator which does not originate with the transformed host cell controls expression of the subject gene and a repressor, which also does not originate with the host cell, regulates the promoter/operator. According to this invention, promoter/operator--repressor functionalities from one bacterium are used in other bacteria, thereby obviating the need to locate homologous expression regulatory sequences for each bacterial host.
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Henner Dennis J.
Yansura Daniel G.
Dreger Walter H.
Genentech Inc.
Hasak Janet E.
Huleatt Jayme A.
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