Chemistry: physical processes – Physical processes – Crystallization
Patent
1980-03-25
1982-04-13
Smith, William F.
Chemistry: physical processes
Physical processes
Crystallization
23913, 422 68, 356 40, G01N 3372
Patent
active
043245560
ABSTRACT:
A portable spectrophotometric apparatus and method therefor for measuring the percentage of carboxyhemoglobin (COHb) in blood. The apparatus comprises a spectrophotometer and wavelength selection filters for testing a reference sample having a hemolizing agent and sodium hyposulfite and a treated blood sample with the hemolizing agent and sodium hyposulfite and providing a two component COHb-Hb system for determining relative absorbance values of the two samples at light wavelengths of 420 nanometers and 432 nanometers, the wavelengths corresponding to respective peak absorbance of the components in the high absorbance Soret region on opposite sides of an isobestic point formed by the intersection of their respective absorbance-wavelength curves. The ratio of the derived relative values is compared against predetermined data to determine the percentage of carboxyhemoglobin in the blood.
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Commins et al., 22 British Journal of Industrial Medicine 139 (1945).
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Rodney et al., Clinical Chemistry, 1388-1393, 1979.
Connor Thomas J.
Robertson Robert F.
Rodkey F. Lee
Smith William F.
The United States of America as represented by the Secretary of
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