Porphyromonas gingivalis 1435/1449 LPS as an immune modulator

Details Porphyromonas gingivalis 1435/1449 LPS as an immune modulator Porphyromonas gingivalis 1435/1449 LPS as an immune modulator

2005-12-13

2009-11-24

Swartz, Rodney P. (Department: 1645)

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

C424S009100, C424S009200, C424S184100, C424S234100, C424S282100, C435S004000, C435S007100, C435S007200

Reexamination Certificate

active

07622128

ABSTRACT:
A preparation containing lipopolysaccharide (LPS) ofPorphyromonas gingivalishaving a molecular negative mass ion of 1435 or 1449 is used as an immune system modulator to redirect a host's immune system against an antigen of interest. The 1435/1449 LPS preparation can be isolated fromP. gingivalisor prepared as a derivative or mimetic thereof. The immunomodulating preparations ofP. gingivalis1435/1449 can be used as a vaccine adjuvant, and can be used to stimulate an immune response against a selected antigen associated with a disease of interest, such an antigen associated with a tumor, infectious disease, autoimmune disease, MHC antigen, or to modulate asthma or other inflammatory conditions.

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