Porphyrin derivatives and their use in photon activation...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

active

07816518

ABSTRACT:
The present invention relates to the use of a compound of formula (I) in the manufacture of a pharmaceuticals composition for cell death by photo activation therapy and the use of the compounds in the prevention and/or treatment of cancer.

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Gassman et al., “Electronic Effects of Peripheral . . . ”, J. Am. Chem. Soc., 1992, 114, 9990-10000.
Samuels et al., “Halogenation of porphyrin . . . ”, J. Chem. Soc., 1968, 145-147.
Osterloh and Vicente, 2002, “Mechanisms of porphyrinoid localization in tumors,”J. Porphyrins and Phthalocyanines, 6:305-24.
Gassman, et al., “Electronic Effects of Peripheral Substituents in Porphyrins: X-ray Photoelectron Spectroscopy and ab Initio Self-Consistent Field Calculations”, J. Am. Chem. Soc. (1992), v. 114, pp. 9990-1000.
Samuels, et al., “Halogenation of Porphin and Octaethylporphin”, J. Chem. Soc. (1968), No. 2, pp. 145-147.
International Search Report (PCT/GB2005/002693) Sep. 30, 2005.

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