Porphyrin and phthalocyanine antiviral compositions

Details Porphyrin and phthalocyanine antiviral compositions Porphyrin and phthalocyanine antiviral compositions

1992-04-24

1994-01-25

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514185, 540122, 540139, 540140, 540145, 530826, A61K 3140

Patent

active

052816168

ABSTRACT:
Compositions for the inhibition of replication of human immunodeficiency virus containing one or more "porphyrins" possessing antiviral activity. As used herein "porphyrins" includes porphyrins, phthalocyanines, chlorins, metallo derivatives thereof, and other porphyrin-like compounds. Examples of natural and synthetic, positively, negatively, and neutrally charged porphyrins, phthalocyanines, and derivatives thereof have been found to exhibit selective anti-HIV activity which is not dependent on the presence of light.

REFERENCES:
patent: 4614723 (1986-09-01), Schmidt et al.
patent: 4649151 (1987-03-01), Dougherty et al.
patent: 4675338 (1987-06-01), Bommer et al.
patent: 5051415 (1991-09-01), Morgan et al.
patent: 5081115 (1992-01-01), Vreman et al.
patent: 5084475 (1992-01-01), Kappas et al.
patent: 5091385 (1992-02-01), Gulliya et al.
patent: 5120649 (1992-06-01), Horowitz et al.

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