Porous spun polymeric structures and method of making same

Adhesive bonding and miscellaneous chemical manufacture – Methods – Surface bonding and/or assembly therefor

Reexamination Certificate

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C156S181000, C156S578000, C156S296000, C156S244110, C156S356000, C156S350000, C156S062400, C118S200000, C118S202000, C210S645000, C210S508000, C264S239000, C264S241000

Reexamination Certificate

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07083697

ABSTRACT:
A non-woven polymeric matrix for separating leukocytes from a blood sample includes a non-woven three dimensional matrix formed from polymeric fibers having a predetermined pore volume fraction including a defined channel configuration, a predetermined pore size in the range of from about 10 μm to about 250 μm, and a plurality of connections between the plurality of fibers. The matrix is configured so as to remove at least about 98% of leukocytes from at least one unit of packed red blood cells. Methods of making and using the matrix are also provided.

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