Porous polymer scaffolds for tissue engineering

Details Porous polymer scaffolds for tissue engineering Porous polymer scaffolds for tissue engineering

1999-04-16

2000-08-15

Foelak, Morton

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

435174, 435180, 435182, 521 61, 521 64, 623 16, A61F 200, C12N 1100, C08J 926, C08J 928

Patent

active

061032557

ABSTRACT:
Biodegradable and biocompatible porous scaffolds characterized by a substantially continuous polymer phase, having a highly interconnected bimodal distribution of open pore sizes with rounded large pores of about 50 to about 500 microns in diameter and rounded small pores less than 20 microns in diameter, wherein the small pores are aligned in an orderly linear fashion within the walls of the large pores. Methods of preparing polymeric tissue scaffolds are also disclosed.

REFERENCES:
patent: 2772322 (1956-11-01), Witt et al.
patent: 2846727 (1958-08-01), Bechtold
patent: 3536796 (1970-10-01), Rock
patent: 4826945 (1989-05-01), Cohn et al.
patent: 5099060 (1992-03-01), Kohn et al.
patent: 5149579 (1992-09-01), Park et al.
patent: 5180751 (1993-01-01), Park et al.
patent: 5198507 (1993-03-01), Kohn et al.
patent: 5216115 (1993-06-01), Kohn et al.
patent: 5332761 (1994-07-01), Paquet et al.
patent: 5369137 (1994-11-01), Paquet et al.
patent: 5514378 (1996-05-01), Mikos et al.
patent: 5587507 (1996-12-01), Kohn et al.
patent: 5658995 (1997-08-01), Kohn et al.
patent: 5670602 (1997-09-01), Kohn et al.
patent: 5686091 (1997-11-01), Leong et al.
patent: 5723508 (1998-03-01), Healy et al.
Reed et al., "Biodegradable Elastomeric Biomaterials-Polyethylene Oxide/Polyethylene Terephthalate Copolymers," Trans. Am. Soc. Artif. Intern. Organs,23 109-114 (1977).
deGroot et al., "Use of porous biodegradable polymer implants in meniscus reconstruction. 1) Preparation of porous biodegradable polyurethanes for the reconstruction of meniscus lesions," Colloid Polym. Sci., 268, 1073-1081 (1990).
Mikos et al., "Preparation and characterization of poly(L-lactic acid) foams," Polymer, 35, 1068-77 (1994).
Laurenein et al., "A highly porous 3-dimensional polyphosphazene polymer matrix for skeletal tissue regeneration," Journal of Biomedical Materials Research, 30, 133-138 (1996).
Schugens et al., "Polylactide macroporous biodegradable implants for cell transplantation. II. Preparation of polylactide foams by liquid-liquid phase separation," Journal of Biomedical Materials Research, 30, 449-461 (1996).

Affiliated with

Also associated with

Rating

Porous polymer scaffolds for tissue engineering does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Porous polymer scaffolds for tissue engineering, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Porous polymer scaffolds for tissue engineering will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2003799