Optics: measuring and testing – With sample preparation – Depositing particles on optical surface
Reexamination Certificate
2011-03-08
2011-03-08
Stafira, Michael P (Department: 2886)
Optics: measuring and testing
With sample preparation
Depositing particles on optical surface
Reexamination Certificate
active
07903239
ABSTRACT:
The invention includes sensors and sensing methods for determining cell morphology and/or chemical composition of an analyte. A porous substrate exhibiting a first optical signal is exposed to a target analyte and subsequently monitored for changes in the optical signal. More specifically, a photonic or porous substrate having a well-defined and highly tunable reflectivity or transmission spectrum, such as porous silicon (Si), porous alumina, porous Ge, porous GaAs, porous SiO2 and porous polymer, is used for example. A porous or photonic substrate is exposed to an analyte, such as a cell or other macromolecule, and changes in the scattered light are observed over time to determine cell morphology and/or chemical composition of the analyte using the substrate.
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Alvarez Sara
Bhatia Sangeeta
Campbell Rebecca
Chao Lin
Derfus Austin
Greer Burns & Crain Ltd.
Stafira Michael P
The Regents of the University of California
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