Porous nanofiber mesh for three-dimensional cell culture

Details Porous nanofiber mesh for three-dimensional cell culture Porous nanofiber mesh for three-dimensional cell culture

2005-12-21

2011-12-06

Naff, David (Department: 1657)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Solid support and method of culturing cells on said solid...

C435S029000, C435S034000, C435S180000

Reexamination Certificate

active

08071382

ABSTRACT:
Disclosed is a mesh for cell culture in which linear nanofiber is cross-linked to form a network, wherein the linear nanofiber is composed of polyhydroxyalkanoate; or polyhydroxyalkanoate, and collagen, gelatin or their mixture. The mesh for cell culture of the present invention can culture cell since the cell, more preferably the cancer cell is easily stuck to the mesh because of its structural characteristics and effect of the added collagen or gelatin, and also to smoothly supply nutrients, oxygen, etc. through connected pores. In particular, the mesh for cell culture of the present invention may be useful to culture the cancer cell.

REFERENCES:
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patent: WO 2005/047493 (2005-05-01), None
Mo et al., “Electrospun P(LLA-CL) nanofiber: a biomimetic extracellular matrix for smooth muscle cell and endothelial cell proliferation,”Biomaterials, vol. 25, Issue 10, 2004 (pp. 1883-1890).
Yoshimoto et al., “A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering,”Biomaterials, vol. 24, No. 12, 2003 (pp. 2077-2082).
PCT International Search Report based on International Application No. PCT/KR2005/004433, date of mailing of the International Search Report Feb. 9, 2006 (2 pgs.).

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