Porous membranes for use with implantable devices

Details Porous membranes for use with implantable devices Porous membranes for use with implantable devices

2007-03-20

2007-03-20

Saucier, Sandra E. (Department: 1657)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Having means to promote cellular attachment

Reexamination Certificate

active

10647065

ABSTRACT:
A membrane for implantation in soft tissue comprising a first domain that supports tissue ingrowth, disrupts contractile forces typically found in a foreign body response, encourages vascularity, and interferes with barrier cell layer formation, and a second domain that is resistant to cellular attachment, is impermeable to cells and cell processes, and allows the passage of analytes. The membrane allows for long-term analyte transport in vivo and is suitable for use as a biointerface for implantable analyte sensors, cell transplantation devices, drug delivery devices, and/or electrical signal delivering or measuring devices. The membrane architecture, including cavity size, depth, and interconnectivity, provide long-term robust functionality of the membrane in vivo.

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