Porin B (PorB) as a therapeutic target for prevention and...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

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C435S007320, C435S069100

Reexamination Certificate

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06899880

ABSTRACT:
The present invention features the use of PorB polypeptide as a therapeutic agent. In specific embodiment the invention features a chlamydial vaccine based on a PorB polypeptide, as well as methods for induction of a protective immune response against infection byChlamydiaandChlamydiophila. The invention further features methods for identifying agents that affect PorB function such as in transport of α-ketoglutarate and which are effective as anti-chlamydial chemotherapeutic agents.

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