Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Inactivation or attenuation; producing viral subunits
Patent
1997-02-24
1999-02-02
Knode, Marian C.
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
Inactivation or attenuation; producing viral subunits
4352351, 435236, 435239, 4241991, 4242041, C12N 708, C12N 701, C12N 700, C12N 702
Patent
active
058664017
ABSTRACT:
The invention discloses a vaccine and methods for the treatment of porcine reproductive and respiratory syndrome. The vaccine is derived from the viral agent NEB-l-P94, deposited at the American Type Culture Collection under accession number VR-2525.
Further, the invention discloses a vaccine virus with phenotypic characteristics which can be distinguished from wild type PRRS virus.
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Yoon et al. "Failure to consider the antigenic diversity of porcine reproductive and respiratory syndrom (PRRSV) virus isolateds may lead to misdiagnosis". J. Vet. Diagn. Invest. vol. 7, pp. 386-387, Jul. 1995.
Nelson et al. "Differential of U.S. and European Isolates of Porcine Reproductive and Respiratory Syndrom Virus by Monoclonal Antibodies". Journal of Clinical Microbiology. vol. 31, No. 12, pp. 3184-3189, Dec. 1993.
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Meng, X.-J. et al., Journal of General Virology, vol. 76, 1995, pp. 3181-3188.
Knode Marian C.
Lee Datquan
Maitner John J.
Mann Arthur
Schering Corporation
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