Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1999-03-25
2000-03-21
Caputa, Anthony C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530395, C07K 1447
Patent
active
060404280
ABSTRACT:
A porcine E-selectin protein, its amino acid sequence, the sequence of a cDNA encoding the protein, antibodies reactive with the protein, and methods for the use of these molecules are disclosed. The molecules are used to diagnose the rejection of xenotransplanted pig organs, as well as to prevent and treat such transplant rejection.
REFERENCES:
Nguyen et al., Nature, vol. 365, pp. 267-269, 1993.
Evans Mark J.
Matis Louis A.
Rollins Scott
Rother Russell P.
Alexion Pharmaceuticals, Inc.
Caputa Anthony C.
Gucker Stephen
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