Porcine adenovirus E1 and E4 regions

Details Porcine adenovirus E1 and E4 regions Porcine adenovirus E1 and E4 regions

2002-07-19

2009-08-04

Marvich, Maria (Department: 1633)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

C424S093700, C424S093600, C435S325000, C435S455000, C435S456000, C435S320100

Reexamination Certificate

active

07569217

ABSTRACT:
The present invention relates to the characterization of the porcine adenovirus E1 and E4 regions. The complete nucleotide sequence of the genome of porcine adenovirus type 3 (PAV-3), providing the characterization of the PAV3 E1 region, is described herein. Methods for construction of infectious PAV genomes by homologous recombination in procaryotic cells are provided. Recombinant PAV viruses are obtained by transfection of mammalian cells with recombinant PAV genomes. The PAV-3 genome can be used as a vector for the expression of heterologous nucleotide sequences, for example, for the preparation and administration of subunit vaccines to swine or other mammals.

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