Population scale HLA-typing and uses thereof

Details Population scale HLA-typing and uses thereof Population scale HLA-typing and uses thereof

2007-02-27

2010-02-23

Kim, Young J (Department: 1637)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S006120, C536S024300

Reexamination Certificate

active

07667026

ABSTRACT:
The present invention provides a portable system for real-time population-scale HLA genotyping and/or allelotyping in a field environment and methods of such population-scale HLA genotyping. The individual components of the system are portable to and operable within a field environment thereby providing high throughput with real-time geno- or allelotyping. Also provided are HLA gene-specific primers and HLA allele-specific or single nucleotide polymorphism-specific hybridization probes. In addition the present invention provides a microarray comprising the hybridization probes. Further provided is a kit comprising the HLA gene-specific primers and the microarray.

REFERENCES:
patent: 4582788 (1986-04-01), Erlich
patent: 5567809 (1996-10-01), Apple et al.
patent: 6670124 (2003-12-01), Chow et al.
patent: 2005/0260662 (2005-11-01), Yang et al.
patent: WO 0106011 (2001-01-01), None

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