Poorly soluble medicaments supported on polymer substances in a

Details Poorly soluble medicaments supported on polymer substances in a Poorly soluble medicaments supported on polymer substances in a

1992-09-28

1993-07-06

Page, T. K.

Drug, bio-affecting and body treating compositions

Topical body preparation containing solid synthetic organic...

424457, 424468, 424449, A61K 3174

Patent

active

052251926

ABSTRACT:
A poorly soluble medicament is incorporated into particles of a crosslinked polymer which is swellable in water but insoluble in water, and the product obtained is brought into contact with a solvent able to swell the polymer. The product obtained by this treatment, and after being dried under vacuum, has a medicament dissolving rate which is considerably higher than that of the pure medicament.

REFERENCES:
patent: 4282209 (1981-08-01), Tocker
patent: 4303642 (1981-12-01), Kangas
patent: 4312855 (1982-01-01), Grand
patent: 4818517 (1989-04-01), Kwee et al.
patent: 4837031 (1989-06-01), Denton
patent: 4882167 (1989-11-01), Jang

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