Stock material or miscellaneous articles – Hollow or container type article – Polymer or resin containing
Patent
1997-05-22
1998-11-24
Nold, Charles
Stock material or miscellaneous articles
Hollow or container type article
Polymer or resin containing
428 344, 428 357, 428 347, 428 367, 204299R, 204451, 204455, 204601, 204605, C25B 900
Patent
active
058403884
ABSTRACT:
A coated microcapillary column for high performance electrophoresis is disclosed. A preferred microcapillary includes a fused silica capillary column, the inner surface of the column having an interconnected polymeric coating of a polyvinyl alcohol (PVA) based polymer covalently attached to the column wall by Si--O--Si bonds. The resulting coated microcapillary column has good hydrolytic and pH stability and minimizes electroosmotic flow and interactions between sample components and the capillary wall. Also disclosed are a method of forming a polymeric coating layer for any surface by polymerizing the appropriate organic compounds in an organic solvent and a method of forming a column with a hydrophilic polymeric coating by directly converting an attached hydrophobic polymeric coating material to a hydrophilic polymeric coating material.
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Goetzinger Wolfgang
Karger Barry L.
Nold Charles
Northeastern University
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