Polyvinyl alcohol ophthalmic gel

Details Polyvinyl alcohol ophthalmic gel Polyvinyl alcohol ophthalmic gel

1978-11-22

1981-03-10

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424148, 424236, 424283, 424273R, 424325, A61K 3174, A61K 3159, A61K 3135, A61K 31415

Patent

active

042554152

ABSTRACT:
An ophthalmic gel having an improved intensity and duration of the biological response is provided by utilizing a polyvinyl alcohol-sodium borate gel buffered to a pH of 6.5-8.5.

REFERENCES:
patent: 2703777 (1955-03-01), Feinstein et al.
patent: 2861920 (1958-11-01), Dale et al.
patent: 3214338 (1965-10-01), Ehrlich
patent: 3608073 (1971-09-01), Phares et al.
patent: 3767788 (1973-10-01), Rankin
patent: 4003991 (1977-01-01), Krohn et al.
Invest. Ophthal. Feb. (1975) 14 (2) pp. 87-89, "Ophthalmic Drug Inserts".
Am. J. Ophthalmol. 57 (1) pp. 99-106 (1964)-Krishna et al., PVA as an Ophthalmic Vehicle.
Symposium on Ocular Therapy, 9 pp. 1-16 (1977), Maichuk-"Polymeric Drug Delivery Systems".
Japanese Published Appli. 7,131,456-Modified PVA Hydrogel Compositions-(1967).

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