Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Patent
1996-09-13
1999-05-11
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
424448, 424486, 424DIG7, 607307, 5147723, A61L15/16
Patent
active
059026030
ABSTRACT:
High capacity drug reservoirs are provided for incorporation into transdermal drug delivery systems. The drug reservoirs are hydrogels formulated from polyurethanes crosslinked with diisocyanate crosslinking agents or cured with radiation in the presence of a photoinitator. Drug loading as high as 65 to 70 wt. % or higher can be achieved by absorbing drug formulation into the reservoir after hydrogel synthesis. Methods for making and using transdermal systems containing such reservoirs are provided as well.
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Chen Tung-Fen
Chiang Chia-Ming
Jona Janan
Joshi Priti
Ramdas Asha
Cygnus Inc.
Horne Angela
McClung Barbara G.
Page Thurman K.
Shelborne Kathryne E.
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