Polysulfated heparins for treating diseases caused by retrovirus

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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A61K 31725

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049668943

ABSTRACT:
Polysulfated heparins are used for the preparation of drugs for the prophylaxis and therapy of diseases caused by retroviruses.

REFERENCES:
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Arch of Aids Research, Band 1, Nr. 1, 1987, Seiten 45-46; N. Yamamoto et al.: "Effect of the Sulfated Polysaccharides on HIV: A Novel Strategy of Chemical Modification for HIV Antivirals".
The Lancet, Band 1, 19, Jun. 1987, Seite 1379; R. Ueno et al.: "Dextran Sulphate, a Potent Anti-HIV Agent in vitro Having Synergism with Zidovudine".
Anticancer Research, Band 7, Nr. 5B, Sep.-Oct. 1987, Seiten 1023-1038; E. De Clercq: "Perspective for the Chemotherapy of AIDS".
Cancer Research, Band 38, Nr. 8, Aug. 1978, Seiten 2401-2407; R. A. DiCioccio et al.: "Inhibition of Deoxynucleotide-Polymerizing Enzyme Activities of Human Cells and of Simian Sarcoma Vir. by Hep.".
Antiviral Research, vol. 7, No. 6, Jul. 1987, 361-367, Elsevier: Masaihiko Ito et al.: "Inhibitory Effect of Dextran Sulfate and Herp. on the Replic. of Human Immuno. Virus (HIV) in Vitro".
The New York Academy of Sciences, Abstracts, Nov. 3-5, 1987, Frederick A. Ofosu, Ph.D. et al.: "Structures and Activities of Heparin and Related Polysaccharides".
Antimicrobial Agents and Chemotherapy, vol. 31, Oct. 1987, No. 10; Robert C. Moellering, Jr. et al.: "Purification and Charac. of an Avian Myeloblastosis and Human Immunodeficiency Virus Reverse . . . ".

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