Polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepi

Details Polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepi Polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepi

1976-01-06

1980-12-09

Tovar, Jose

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

424250, C07D40904

Patent

active

042386110

ABSTRACT:
Polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepine and processes for the preparation thereof are described. The compositions evidence psychotropic and antimicrobial characteristics and are of low toxicity. The described compounds are of the general formula ##STR1## wherein R.sup.2, R.sup.3, R.sup.7 and R.sup.8 are selected from among hydrogen, fluorine and chlorine atoms, a fluoromethyl group, a methoxy group and a hydroxyl group, at least three of R.sup.2, R.sup.3, R.sup.7 and R.sup.8 being other than hydrogen, R being selected from among hydrogen, alkyl or alkylhydroxy groups having from 1-3 carbon atoms, an acyloxyalkyl group having from 8-10 carbon atoms in the acyl moiety and from 2-3 carbon atoms in the alkyl moiety and an ethoxycarbonyl group, m and n representing integers from 0-1 and the bond between the 10 and 11 carbon atoms being either a single or double bond.

REFERENCES:
patent: B539374 (1976-03-01), Gerecke et al.
patent: 3928383 (1975-12-01), Kaplan et al.
patent: 3954769 (1976-05-01), Gerecke et al.
patent: 3966737 (1976-06-01), Gerecke et al.
patent: 4011222 (1977-03-01), Gerecke et al.

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