Polysaccharides and preparation thereof

Details Polysaccharides and preparation thereof Polysaccharides and preparation thereof

1995-09-29

1998-05-26

Lankford, Jr., Leon B.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

53612312, 5361231, 536124, 536126, 536102, 536107, C12P 1904, C07H 100, C08B 3700, C08B 3718

Patent

active

057563187

ABSTRACT:
A novel polysaccharide comprising (1->4) bonded .alpha.-D-glucose units represented by the following formula ##STR1## wherein R is a hydrogen atom or an acetyl group in a ratio of 7:3 is extracted and isolated from a liquid culture medium of a microorganism belonging to the class Basidiomycetes in the presence of a plant tissue extract. About 30% by mole of hydroxyl groups at the 2,3-positions of each unit is acetylated and the polysaccharide has a molecular weight of 500 to 10,000. The polysaccharide has properties of biological response modifiers (BRM) and is useful as an immuno-enhancing agent or immuno-activator.

REFERENCES:
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patent: 4200693 (1980-04-01), Yokobayashi et al.
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patent: 4614733 (1986-09-01), Yoshikumi et al.
patent: 4959466 (1990-09-01), White
Singleton, Dictionary of Microbiology and Molecular Biology, 2nd Ed. 1987, pp. 102-103.

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