Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Reexamination Certificate
2007-08-07
2007-08-07
Devi, S. (Department: 1645)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
C424S237100, C424S184100, C424S831000, C536S123100, C536S127000, C514S023000, C514S054000, C514S062000
Reexamination Certificate
active
09771003
ABSTRACT:
The invention relates to compositions of the capsular polysaccharide/adhesin (PS/A) ofstaphylococci. The PS/A may be isolated or synthesized and includes various modifications to the structure of native PS/A based on the chemical characterization of PS/A. The invention also relates to the use of the PS/A as a vaccine for inducing active immunity to infections caused byStaphylococcus aureus, S. epidermidis, other related coagulase-negativestaphylococciand organisms carrying the ica (intracellular adhesin) locus, and to the use of antibodies directed to PS/A for inducing passive immunity to the same class of infections.
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Locksley, R.M., ȁ
McKenney David
Pier Gerald B.
Wang Julia Y.
Devi S.
The Brigham and Women's Hospital, Inc.
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