Polypyridine Fluorescent labels for immunoassay

Details Polypyridine Fluorescent labels for immunoassay Polypyridine Fluorescent labels for immunoassay

1987-04-20

1989-06-06

Schwartz, Richard A.

Chemistry: analytical and immunological testing

Involving producing or treating antigen or hapten

Producing labeled antigens

25230116, 25230117, 25230118, 424 71, 435 4, 435 7, 436800, 546 2, G01N 2164

Patent

active

048371696

ABSTRACT:
There are described stable fluorescent labels comprising a complex of Eu.sup.+3 and a chelating agent comprising a nucleus which is a triplet sensitizer having a triplet energy greater than that of Eu.sup.+3 and at least two heteroatom-containing groups which form coordinate complexes with Eu.sup.+3 and a third heteroatom-containing group or heteroatom in or appended to the triplet sensitizer. Labeled physiologically active materials useful in specific binding assays such as labeled antigens, haptens, antibodies, hormones and the like comprising the stable fluorescent labels having physiologically active materials adsorbed or bonded thereto are also described.

REFERENCES:
patent: 4058732 (1977-11-01), Wieder
patent: 4259313 (1981-03-01), Frank et al.
patent: 4283382 (1981-08-01), Frank et al.
patent: 4352751 (1982-10-01), Wieder et al.
Chemical Abstracts, 82:38148k (1975) [Busev, A. et al., ZH. Anal. Khim., 1974, 29(8) 1474-7].

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