Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1984-12-04
1987-01-27
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544176, A61K 31535, C07D29518
Patent
active
046394508
ABSTRACT:
This invention relates to polyprenylcarboxylic acid amides represented by the following general formula (I): ##STR1## wherein n is an integer of from 1 to 4, a and b stand for hydrogen atoms or a direct valence bond between the carbon atoms to which a and b are attached, c and d stand for hydrogen atoms or a direct valence bond between the carbon atoms to which c and d are attached, and R.sub.1 and R.sub.2 stand for a hydrogen atom, a lower alkyl group, a phenyl group which may be substituted or an aralkyl group which may be substituted, or R.sub.1 and R.sub.2 form, together with the adjacent nitrogen atom, a 5- or 6-membered heterocyclic ring which may contain other hetero atoms or may be substituted,
and also to a process for the preparation of said polyprenylcarboxylic acid amide and to a pharmaceutical composition for treating liver dysfunction comprising said polyprenylcarboxylic acid amide.
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patent: 3294794 (1966-12-01), Holmes et al.
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patent: 3621043 (1971-11-01), Seki et al.
patent: 3649590 (1972-03-01), Siddall
patent: 3773805 (1973-11-01), Siddall
Abe Shinya
Hara Kumiko
Igarashi Toshiji
Inai Yuichi
Shiojiri Hiroyuki
Eisai Co. Ltd.
Ramsuer Robert W.
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