Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1996-02-23
1999-09-21
Mosher, Mary E.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
435 691, 4352351, 4353201, 530350, 536 2372, 536 234, A61K 3912, C12P 2106, C07H 2104
Patent
active
059550872
ABSTRACT:
Fusion polypeptides and aggregates of polypeptides comprising papillomavirus-derived antigens, and compositions thereof and their use e.g. with adjuvants for immunogenic and vaccine purposes in eliciting e.g. HPV-specific immune responses. The polypeptides can be purified to result in aggregates which when in solution or dispersion can pass through a sterilisation filter, and in amorphous aggregates. An example of such a polypeptide is a fusion protein of human papillomavirus proteins L2 and E7.
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Carmichael Jeremy Paddon
Connor Stephen Edward
Thompson Henry Stephen Grammer
Whittle Nigel Richard
Wilson Mark Jonathan
Cantab Pharmaceuticals Research Limited
Mosher Mary E.
Salimi Ali R.
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