Polypeptides that bind HIV gp120 and related nucleic acids,...

Details Polypeptides that bind HIV gp120 and related nucleic acids,... Polypeptides that bind HIV gp120 and related nucleic acids,...

2007-12-04

2007-12-04

Parkin, Jeffrey S. (Department: 1648)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

15 to 23 amino acid residues in defined sequence

Reexamination Certificate

active

10084813

ABSTRACT:
The present invention provides, among other things, a polypeptide that binds with the gp120 envelope protein of HIV, in particular HIV-1, under physiological conditions, a nucleic acid that encodes such a polypeptide and can be expressed in a cell, a composition comprising such a polypeptide or nucleic acid or an antibody and a carrier therefor, a composition comprising a solid support matrix to which is attached an above-described polypeptide or an anti-antibody to a specified polypeptide sequence, a method of making an antibody to gp120, and a method of removing HIV from a bodily fluid.

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Chan et al.,Journal of Virology 73(3): 2350-2358 (Mar. 1999).
Farzan et al.,Journal of Virology 72(2): 1160-1164 (Feb. 1988).
Shapira-Nahor et al.,Cellular Immunology 128:101-117 (1990).

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