Polypeptides of the IFNα-21 gene

Drug – bio-affecting and body treating compositions – Lymphokine – Interferon

Reexamination Certificate

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C530S351000

Reexamination Certificate

active

10673886

ABSTRACT:
Polynucleotides and polypeptides derived from the nucleotide sequence of the IFNα-21 gene comprising SNPs, and their therapeutic uses.

REFERENCES:
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patent: WO 00/39280 (2000-07-01), None
patent: WO 01/25438 (2001-04-01), None
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H. Weber et al., “Single amino acid changes that render human IFN-α2 biologically active on mouse cells,” The EMBO Journal, vol. 6, No. 3, pp. 591-598, 1987.
Ann-Christine Syvänen et al., “Identification of Individuals by Analysis of Biallelic DNA Markers, Ising PCR and Solid-Phase Minisequencing,” Am. J. Genet., vol. 52, pp. 46-59, 1993.
Musaddeq Hussain et al., “Identification of Interferon-α7, -α14, and -α21 Variants in the Genome of a Large Human Population,” Journal of Interferon And Cytokine Research, vol. 16, pp. 853-859, (1996).
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Ryo Yamada et al., “Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population,” Hum. Genet. (2000), vol. 106, pp. 293-297.
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International Search Report dated Jun. 13, 2003 for Application No. PCT/EP02/04082.
Accession No. NM—002175 “Homo sapiensinterferon, alpha 21 (IFNA21), mRNA” (1998).
Accession No. AC009445 “Homo sapiensclone PR11-1P8” (Sep. 10, 2000).
Swiss-Prot entry P05007 “Interferon alpha-A [Precursor]” (Aug. 13, 1987).

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