Polypeptides of the IFNα-17 gene

Details Polypeptides of the IFNα-17 gene Polypeptides of the IFNα-17 gene

2008-05-13

2008-05-13

Saoud, Christine J (Department: 1647)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C424S085700, C514S002600

Reexamination Certificate

active

10691653

ABSTRACT:
The present invention relates to new polynucleotides derived from the nucleotide sequence of the IFNα-17 gene comprising new SNPs, and new polypeptides derived from the natural wild-type IFNα-17 protein comprising at least one mutation caused by at least one SNP of the invention, as well as their therapeutic uses.

REFERENCES:
patent: 6299877 (2001-10-01), Chen et al.
patent: WO 00/39280 (2000-07-01), None
patent: WO 01/25438 (2001-04-01), None
Ngo et al., 1994, The Protein Folding Problem and Tertiary Structure Prediction, pp. 492-495.
Wells, Aditivity of Mutational Effects in Protiens, 1990, Biochemistry, vol. 26, No. 37, pp. 8509-8517.
International Search Report dated Jun. 13, 2003 for Application No. PCT/EP02/05229.
NCBI Sequence Viewer, Human gene for leukocyte (alpha) interferon C., ABSTRACT, 2 pages.
“DNA Sequence of Two Closely Linked Human Leukocyte Interferon Genes,” Science, vol. 212, Jun. 5, 1981, pp. 1159-1162.
K. Henco1,a, “Structural Relationship of Human Interferon Alpha Genes and Pseudogenes,” J. Mol. Biol. (1995) vol. 185, pp. 227-260.
Axel Ullrich et al., “Nucleotide Sequence of a Portion of Human Chromosome 9 Containing a Leukocyte Interferon Gene Cluster,” J. Mol. Biol. (1982) 156, pp. 467-486.
Ann-Christine Syvanen et al., “Identification of Individuals by Analysis of Biallelic DNA Markers, Ising PCR and Solid-Phase Minisequencing,” AM. J. Genet., vol. 52, pp. 46-59, 1993.
H. Weber et al., “Single amino acid changes that render humna IFN-α2 biologically active on mouse cells,” The EMBO Journal, vol. 6, No. 3, pp. 591-598, 1987.
Musaddeq Hussain et al., “Indentification of Interferon-α7, -α14, and -α21 Variants in the Genome of a Large Human Population,” Journal of Interferon And Cytokine Research, vol. 16, pp. 853-859, (1996).
Rob L. H. Jansen et al., “Interleukin-2 and Interferon-α in the Treatment of Patients with Advanced Non-Small-Cell Lung Cancer,” Journal Of Immunotherapy, vol. 12, No. 1, 1992, pp. 70-73.
Eiji Mita et al., “Predicting Interferon Therapy Efficacy from Hepatitis C Virus Genotype and RNA Titer,” Digestive Diseases and Science, vol. 39, No. 5, (May 1994), pp. 977-982.
Ryo Yamada et al., “Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population,” Hum. Genet. (2000), vol. 106, pp. 293-297.
S. Cohen et al., “Cloning, Expression and Biological Activity of a New Variant of Human Interferon α Identified in Virus Induced Lymphoblastoid Cells,” Develop. Biol. Standard., vol. 60, pp. 111-122, 1985.
O. I. Olopade et al., “Mapping of the Shortest Region of Overlap of Deletions of the Short Arm of Chromosome 9 Associated with Human Neoplasia,” Genomics 14, pp. 437-443 (1992).

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