Polypeptides of an IL-1-like cytokine

Details Polypeptides of an IL-1-like cytokine Polypeptides of an IL-1-like cytokine

2006-09-19

2006-09-19

Mertz, Prema (Department: 1646)

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

C530S351000, C435S810000, C435S975000

Reexamination Certificate

active

07108850

ABSTRACT:
Nucleic acids encoding mammalian, e.g., primate, IL-1ζ, purified IL-1ζ polypeptides and fragments thereof. Binding proteins, e.g., antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.

REFERENCES:
patent: 5194596 (1993-03-01), Tischer et al.
patent: 0 541 920 (1993-05-01), None
patent: 0 855 404 (1998-07-01), None
patent: WO 99/06426 (1999-02-01), None
patent: WO 99/07850 (1999-02-01), None
patent: WO 99/36541 (1999-07-01), None
Skolnick et al., 2000, Trends in Biotech. 18; 283-287.
Benjamin et al., 1998, Development. 125;1591-1598.
Vukicevic et al., 1996, PNAS USA 93:9021-9026.
Kumar et al., 2000, J. Biol. Chem. 275:10308-10314.
P.E. Auron, et al., GenPept, Accession No. 124303, Jul. 15, 1998. Definition: Interleukin-1 Beta Precursor (IL-1 Beta) (CATABOLIN).
Gregory J. Bancroft, et al., Immunol. Reviews, 124:5-24, 1991. “Natural Immunity: A T-Cell-Independent Pathway of Macrophage Activation, Defined in the scid Mouse”.
J. Fernando Bazan, et al., Nature, 379:591, Feb. 15, 1996. “A newly defined interleukin-1?”.
Marcia P. Belvin, et al., Annu. Rev. Cell Dev. Biol., 12:393-416, 1996. “A conserved signaling pathway; The Drosophila TollDorsal Pathway”.
M.J. Carrier, Genbank, Accession No. X64532, Jun. 25, 1997. Definition: “H.sapiens gene for interleukin-1 receptor antagonist”.
D.B. Carter, et al., GenPept, Accession No. 124312, Jul. 15, 1998. Definition: Interleukin-1 receptor antagonist protein precursor (IL-1RA) (ICIL-1RA) (IRAP).
Fabio Cominelli, et al., J. Biol. Chem., 296(9):6962-6971, Mar. 4, 1994. “Rabbit Interleukin-1 Receptor Antagonist”.
F. Cominelli, et al., GenBank, Accession No. S68977, Sep. 22, 1994. Definition: “sIL-1ra=interleukin-1 receptor antagonist secreted form [rabbits, colon tissue, mRNA, 574 nt.]”.
Charles A. Dinarello, Blood, 77(8):1627-1652, Apr. 15, 1991. “Interleukin-1 and Interleukin-Antagonism”.
Charles A. Dinarello, The FASEB Journal, 8:1314-1325, Dec. 1994. “The interleukin-1 family: 10 years of discovery”.
Charles A. Dinarello, Blood, 87(6):2095-2147, Mar. 15, 1996. “Biologic Basis for interleukin-1 in Disease”.
W.H. Gilmore, et al., GenBank, Accession No. Z70047, Mar. 11, 1996. Definition: “C.familiaris mRNA for interleukin-1 beta”.
F. Goto, et al., GenBank, Accession No. D21832, Apr. 21, 1994. Definition: “Rabbit mRNA for interleukin-1 receptor antagonist, complete cds.”.
Angela M. Gronenborn and G. Marius Clore, Protein Engineering, 4(3):263-269, 1991. “Modeling the three-dimensional structure of the monocyte chemo-attractant and activating protein MCAF/MCP-1 on the basis of the solution structure of interleukin-8”.
H. Hamada and R.C. Mulligan, et al., GenBank, Accession No. M57526, Jan. 30, 1992. Definition: “Rabbit interleukin-1 receptor antagonist (IL1RA) mRNA, complete cds.”.
Steven K. Hanks, et al., Methods in Enzymology, 200:38-62, 1991. “[2] Protein Kinase Catalytic Domain Sequence Database: Identification of Conserved Features of Primary Structure and Classification of Family Members”.
C.H. Hannon, et al., GenBank, Accession No. I09591, Nov. 14, 1994. Definition: “Sequence 1 from Patent WO 8911540”.
C.H. Hannon, et al., GenBank, Accession No. I09592, Nov. 14, 1994. Definition: “Sequence 3 from Patent WO 8911540”.
Dan Hultmark, Nature, 367:116-117, Jan. 13, 1994. “Ancient Relationships”.
C.A. Hunter, et al., J. Immunology, 155:4347-4345, 1995. “IL-1β Is Required for IL-12 to induce Production of IFN-γ by NK Cells. A Role for IL-1β in the T Cell-Independent Mechanism of Resistance Against Intracellular Pathogens.”.
J.K. Jenkins, et al., GenBank, Accession No. U65590, Dec. 22, 1997. Definition: “Homo sapiens IL-1 receptor antagonist IL-1Ra (IL-1RN) gene, alternatively spliced forms, complete cds.”.
Bruno Lemaitre, et al., Cell, 86:973-983, Sep. 20, 1996. “The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults”.
S.R. Leong. GenBank, Accession No. X12497, Mar. 13, 1995. Definition: “Bovine mRNA for interleukin-1 alpha”.
Patricia J. Lodi, et al., Science, 263:1762-1767, Mar. 25, 1994. “High—Resolution Structure of the β Chemokine hMIP-1β by Multidimensional NMR”.
C.R. Maliszewski, GenBank, Accession No. X52731, Mar. 31, 1995. Definition: “Pig mRNA for interleukin 1-alpha”.
C.J. March, et al., GenPept, Accession No. 124297, Oct. 1, 1996. Definition: “Interleukin-1 alpha precursor (IL-1 alpha (hematopoietin-1))”.
M. Marra, et al., GenBank, Accession No. AA030324, Jan. 21, 1997. Definition: “mi08c10.r1 Soares mouse placenta 4NbMP13.5 14.5 Mus musculus cDNA clone 459858 5′, mRNA sequence”.
M. Marra, et al., GenBank, Accession No. W08205, Sep. 5, 1996. Definition: “mb49b11.r1 Soares mouse p3NMF19.5 Mus musculus cDNA clone 332733 5′ similar to PIR:A49031 A49031 interleukin 1 receptor antagonist—mouse ; mRNA sequence”.
Y. Masaaki, et al., GenBank, Accession No. E01109, Nov. 26, 1996. Definition: “cDNA sequence of human IL-1”.
Y. Masaaki, et al., GenBank, Accession No. E01442, Nov. 26, 1996. Definition: “cDNA encoding human IL-1”.
Catherine J. McMahan, et al., The EMBO Journal, 10(10):2821-2832, Oct. 1991. “A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types”.
Donald Morisato & Kathryn V. Anderson, Annu. Rev. Genetics, 29:371-399, 1995. “Signaling pathways that establish the dorsal-ventral pattern of the Drosophilia embryo”.
T. Nishida, et al., GenBank, Accession No. D00403, Jan. 19, 1992. Definition: “Rat interleukin-1 alpha mRNA, complete cds.”.
Haruki Okamura, et al., Nature, 378:88-91, Nov. 2, 1995, “Cloning of a new cytokine that induces IFN-g production by T Cells”.
Joost J. Oppenheim, et al., Ann. Rev. Immunol. 9:617-648, 1991. “Properties of the novel proinflammatory supergene ‘intercrine’ cytokine family”.
Laura L. Parker, et al., Nature, 363:736-738, Jun. 24, 1993. “Phosphorylation and inactivation of the mitotic inhibitor Wee1 by the nim1/cdr1 kinase”.
Helge Rothe, et al., The Journal of Clinical Investigation, 93(3):469-474, Feb. 1997. “Active Stage of Autoimmune Diabetes Is Associated with the Expression of a Novel Cytokine, IGIF, Which Is Located Near Idd2”.
Roger A. Sayle & E. James Milner- White, Tibs, 20:374-376, Sep. 1995. “RASMOL: biomolecular graphics for all”.
H.F. Seow, GenBenk, Accession No. X56972, May 26, 1992. Definition: “Ovine IL-1 beta mRNA for interleukin-1 beta”.
Dirk E. Smith, et al. J. Biol. Chem. 275(2):1169-1175, Jan. 14, 2000. “Four new members expand the interleukin-1 superfamily”.
Robert Strausberg (NCI-CGAP), GenBank, Accession No, AI014548, Aug. 27, 1998. Definition: “ou40f01.x1 Soares—NFL—T—GBC—S1 Homo Sapiens cDNA clone IMAGE:1628761 3′, mRNA sequence.”.
J.L. Telford, et al., GenBank, Accession No. X04964, Sep. 16, 1994. Definition: “Murine interleukin-1 beta gene”.
Julie D. Thompson, et al., Nucleic Acids Research, 25(24):4876-4882, 1997. “The Clustal—X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools.”.
K. Totsuka, et al., GenBank, Accession No. D63353, Feb. 13, 1997. Definition: “Cynomolgus monkey mRNA for interleukin-1-beta”.
S. Ushio, et al., GenPept, Accession No. 1405319, Jul. 5, 1996. Definition: “Interferon-gamma inducing factor (IGIF)”.
K. Zahedi, et al., GenBank, Accession No. M74294, Aug. 23, 1991.

Affiliated with

Also associated with

Rating

Polypeptides of an IL-1-like cytokine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polypeptides of an IL-1-like cytokine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polypeptides of an IL-1-like cytokine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3550563