Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1997-11-28
2000-01-11
Horlick, Kenneth R.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
4353201, 435325, 536 237, C12N 121, C07H 2104, C07H 2102
Patent
active
060135085
ABSTRACT:
The invention relates to compositions and nucleic acids encoding polypeptides involved in the expression of resistance to glycopeptides, in particular to vancomycin and/or teicoplanin. The invention also relates to vectors containing said nucleic acids, transformed host cells and their use for the diagnosis of resistance to glycopeptides.
REFERENCES:
patent: 5770361 (1998-06-01), Arthur et al.
T. I. Nicas et al., "Activity of Glycopeptides Against Vancomycin-Resistant Gram-Positive Bacteria", Antimicrob Agents and Chemotherapy, vol. 33, No. 9, pp. 1477-1481, Sep. 1989.
Thalia I. Nicas et al., "Characterization of Vancomycin Resistance in Enterococcus faecium and Enterococcus faecalis", Antimicrobial Agents and Chemotherapy, vol. 33, No. 7, pp. 1121-1124, Jul. 1989.
A. Brisson-Noel et al., "Cloning and Heterospecific Expression of the Resistance Determinant vanA Encoding High Level Resistance to Glycopeptides in Enterococcus faecium BM4147", Antimicrobian Agents and Chemotherapy, vol. 34, No. 5, pp. 924-927, May 1990.
S. Dutka-Malen et al., "Phenotypic and Genotypic Heterogeneity of Glycopeptide Resistance Determinants in Gram-Positive Bacteria", Antimicrobian Agents and Chemotherapy, vol. 34, No. 10, pp. 1875-1879, Oct. 1990.
R. Leclercq et al., "Transferable Vancomycin and Teicoplanin Resistance in Enterococcus faecium", Antimicrobian Agents and Chemotherapy, vol. 33, No. 2, pp. 10-15, Jan. 1989.
S. Dutka-Malen et al., "The Vana Glycopeptide Resistance Protein is Related to D-Alanyl-D-Alanine Ligase Cell Wall Biosynthesis Enzymes", Mol. Gen. Genet., vol. 224, No. 3, pp. 364-372, Dec. 1990.
T.D.H. Bugg et al., "Identification of Vancomycin Resistance Protein Vana as a D-Alanine: D-Alanine Ligase of Altered Substrate Specificity", Biochemistry, vol. 30, No. 8, pp. 2017-2021, Feb. 26, 1991.
Arthur C. Robinson et al., "Further Evidence for Overlapping Transcriptional Units in an Escherichia coli Cell Envelope-Cell Division Gene Cluster: DNA Sequence and Transcriptional Organization of the ddl ftsQ Region", Journal of Bacteriology, vol. 167, No. 3, pp. 809-817, Sep. 1986.
Elisabeth Daub et al., "Isolation, Cloning, and Sequencing of the Salmonella typhimurium ddlA Gene with Purification and Characterization of its Product, D-Alanine:D-Alinine Ligase (ADP Forming)", Biochemistry, Vo. 27, pp. 3701-3708, 1988.
Umesh Varshney et al., "Sequence Analysis, Expression, and Conservation Of Escherichia coli Uracil DNA Glycosylase and its Gene (UNG)", The Journal of Biological Chemistry, vol. 263, No. 16, pp. 7776-7784, 1988.
Michel Arthur et al., "Structural Relationship Between the Vancomycin Resistance Protein VanH and 2-Hydroxycarboxylic Acid Dehydrogenases", Gene, vol. 103, pp. 133-134, 1991.
Arthur Michel
Courvalin Patrice
Dukta-Malen Sylvie
Molinas Catherine
Horlick Kenneth R.
Institut Pasteur
LandOfFree
Polypeptides implicated in the expression of resistance to glyco does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polypeptides implicated in the expression of resistance to glyco, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polypeptides implicated in the expression of resistance to glyco will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1461629