Polypeptides having phospholipase B activity and nucleic acids e

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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435 691, 435183, 435195, 530350, 530371, C12N 914, C12N 920

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active

06146869&

ABSTRACT:
The present invention relates to isolated polypeptides having phospholipase B activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.

REFERENCES:
Leidich et al., Cloning and Disruption of caPLB1, a Phospholipase B Gene Involved in the Pathogenicity of Candida albicans, J. Biol. Chem. 273 (40): 26078-26086, Oct. 1998.
Sugiyama et al. Molecular Coning of a second phospholipase B gene, caPLB2 from Candida albicans, Nedical Mycology 37: 61-67, Sep. 1998.
Memon et al., Phospholipase B activity in mycelia of Asperigillus niger, FEMS Microbiology Letters 18: 15-18, 1983.
Masuda et al., Primary structure of the protein moiety of Penicillium notatum phospholipase B deduced from the cDNA, Eur. J. Biochem. 202: 783-787, 1991.
Masuda et al., Primary structure of the protein moiety of Penicillium notatum phospholipase B decuded from the cDNA, Eur. J. Biochem. 202: 783-787, Oct. 1998.

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